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January 1987

Acute Renal Failure in Cirrhosis Associated With Macroscopic Hematuria of Glomerular Origin

Author Affiliations

From the Departments of Nephrology (Drs Praga, Miranda, and Rodicio), Internal Medicine (Drs Costa and Shandas), and Pathology (Dr Martinez), Hospital 1° de Octubre, Instituto Nacional de la Salud, Madrid.

Arch Intern Med. 1987;147(1):173-174. doi:10.1001/archinte.1987.00370010171036

• Two patients with alcoholic cirrhosis developed an acute Impairment of renal function during an episode of macroscopic hematuria, one of them requiring hemodialysis treatment. Later, when gross hematuria disappeared, renal function gradually improved. The histological findings in both patients showed a mild mesangial glomerulonephritis with IgA deposits on immunofluorescence, the presence of red blood cells casts obstructing the lumen in 40% to 50% of the renal tubules, and a marked tubular necrosis.

(Arch Intern Med 1987;147:173-174)