This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Drs Rosner and Zarrabi are, of course, correct that splenectomy has been cited as a risk factor for both acquiring and dying of pneumococcal infections. In our population, one patient and one control subject had undergone a splenectomy. While the rate of splenectomy in the patients with pneumococcal infections is somewhat higher than in the uninfected control subjects (1.6% vs 0.8%), this difference is too small to achieve statistical significance. Thus, we cannot comment on splenectomy as a risk factor for acquiring pneumococcal infections based on the data obtained from our study.
Lipsky BA. Risk Factors for Acquiring Pneumococcal Infections-Reply. Arch Intern Med. 1987;147(2):212. doi:10.1001/archinte.1987.00370020032026