• An 89-year-old man with chronic glaucoma received hourly pilocarpine eye drops for seven hours, when he developed third-degree atrioventricular block with a slow idioventricular escape rate. After discontinuing the pilocarpine, the atrioventricular block gradually disappeared. The site of pilocarpine-related block was most likely within the His-Purkinje system.
(Arch Intern Med 1987;147:586-587)
Littmann L, Kempler P, Rohla M, Fenyvesi T. Severe Symptomatic Atrioventricular Block Induced by Pilocarpine Eye Drops. Arch Intern Med. 1987;147(3):586-587. doi:10.1001/archinte.1987.00370030184036