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—Cefazolin sodium should have provided effective therapy for 22 (41%) of 53 episodes for which reliable culture results were available. Addition of oral metronidazole therapy would have increased the coverage of cefazolin to 26 (49%) of 53. An alternative regimen of parenteral ceftriaxone and oral metronidazole therapy should provide adequate coverage for 36 (68%) of 53 episodes. The daily cost of these regimens at one of our hospitals is as shown in the Table.
Wheat LJ. Choice of Antibiotics in Diabetic Foot Ulcers-Reply. Arch Intern Med. 1987;147(3):615. doi:10.1001/archinte.1987.00370030212051