July 1987

Nephrotoxicity of Common Drugs Used in Clinical Practice

Author Affiliations

From the Division of Nephrology, School of Medicine, Yale University, New Haven, Conn (Dr Cooper), and the Division of Nephrology and Hypertension, Oregon Health Sciences University, Portland (Dr Bennett).

Arch Intern Med. 1987;147(7):1213-1218. doi:10.1001/archinte.1987.00370070027003

• Drug-induced nephrotoxicity is an increasingly recognized complication of a wide variety of therapeutic agents. The nephrotoxicity of three of the most commonly used drug groups are reviewed in this article. They include antibiotics, radiocontrast agents, and nonsteroidal anti-inflammatory drugs. Since the clinical spectrum of drug-induced nephrotoxicity is broad, it is imperative that the clinician recognize these nephrotoxic syndromes while they are reversible with discontinuation of the offending drug.

(Arch Intern Med 1987;147:1213-1218)