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July 1987

Clinical and Epidemiologic Features of StrongyloidiasisA Prospective Study in Rural Tennessee

Author Affiliations

From the Section of Infectious Diseases, Veterans Administration Medical Center (Drs Berk, Verghese, Alvarez, and Smith), and the Department of Internal Medicine, East Tennessee State University, College of Medicine (Drs Berk, Verghese, Alvarez, Hall, and Smith), Johnson City.

Arch Intern Med. 1987;147(7):1257-1261. doi:10.1001/archinte.1987.00370070071011

• Hospitalized and domiciliary patients were studied to determine the incidence of the endemic nematode Strongyloides stercoralis in stool samples. Strongyloides was found in 14 (6.1%) of 229 hospitalized patients and in nine (2.6%) of 346 domiciliary patients. Clinical symptoms, laboratory data, and underlying diseases were compared for stool-positive and stool-negative patients. Infected patients were more likely to complain of abdominal bloating. They had a higher incidence of eosinophilia and guaiac-positive stools. They were more likely to have been treated with corticosteroids, cimetidine, and antacids. Efficacy of treatment with thiabendazole was studied in all stool-positive patients; a relapse rate of 15% was noted with standard thiabendazole therapy.

(Arch Intern Med 1987;147:1257-1261)