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August 1987

Lactic Acidosis and Insulin Resistance Associated With Epinephrine Administration in a Patient With Non—Insulin-Dependent Diabetes Mellitus

Author Affiliations

From the Endocrine Research Unit, Division of Endocrinology and Metabolism (Drs Caruso and Miles), and Section of Thoracic and Cardiovascular Surgery (Dr Orszulak), Mayo Clinic and Mayo Medical School, Rochester, Minn.

Arch Intern Med. 1987;147(8):1422-1424. doi:10.1001/archinte.1987.00370080058013

• Epinephrine raises plasma lactate concentrations when infused intravenously in normal subjects. We studied a patient with non—insulin-dependent diabetes mellitus who developed lactic acidosis and marked insulin resistance when treated with epinephrine after open heart surgery.

(Arch Intern Med 1987;147:1422-1424)