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December 1987

High-Dose Intravenous ?-Immunoglobulin Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura

Author Affiliations

From the Department of Medicine, Division of Hematology/Oncology, Brookdale Hospital Medical Center, Brooklyn, NY.

Arch Intern Med. 1987;147(12):2165-2167. doi:10.1001/archinte.1987.00370120101017

† Thrombotic thrombocytopenic purpura has been treated with plasmapheresis, exchange transfusion, splenectomy, antiplatelet compounds, glucocorticoids, and vincristine sulfate infusion. We describe a patient with thrombotic thrombocytopenic purpura who has failed on treatment with plasmapheresis, antiplatelet compounds, glucocorticoids, and vincristine, was successfully treated with high-dose γ-immunoglobulin infusion, and has been maintained in prolonged remission without further immunoglobulin infusion for more than 14 months at the time of this report.

(Arch Intern Med 1987;147:2165-2167)