• Pancytopenia Is a well-recognized manifestation of clinical Illness related to human immunodeficiency virus infection. The mechanism of this has been debated, but has been thought to relate either to a nonspecific marrow suppressive effect of opportunistic infections, or to direct involvement of bone marrow hematopoietic precursors as a target of human immunodeficiency virus. We report the unique temporal association of the acquired immunodeficiency syndrome and paroxysmal nocturnal hemoglobinuria.
(Arch Intern Med 1988;148:212-213)
Baumann MA, Pacheco J, Paul CC, Sorg T, Hillman N. Paroxysmal Nocturnal Hemoglobinuria Associated With the Acquired Immunodeficiency Syndrome. Arch Intern Med. 1988;148(1):212-213. doi:10.1001/archinte.1988.00380010214023