April 1988

Streptokinase Dissolution of a Right Atrial Thrombus Associated With a Temporary Pacemaker

Author Affiliations

From the Department of Medicine, Cardiology Section, Mount Sinai Hospital, Hartford, Conn, and the Department of Medicine, University of Connecticut School of Medicine, Farmington.

Arch Intern Med. 1988;148(4):903-904. doi:10.1001/archinte.1988.00380040143020

• Thrombosis of intravascular catheters is a well-recognized and potentially serious complication, which has been treated successfully with thrombolytic agents. A routine echocardiogram in a patient with a temporary transvenous pacemaker demonstrated a large thrombus attached to the pacing electrode. This was dissolved successfully and uneventfully with high-dose intravenous streptokinase therapy. To our knowledge, this is the first report of the successful lysis of a right atrial thrombus complicating a temporary transvenous pacemaker.

(Arch Intern Med 1988;148:903-904)