May 1988

Presumptive Evidence for Blastocystis hominis as a Cause of Colitis

Author Affiliations

From the Departments of Medicine (Drs Russo, Stone, and Taplin and Mr Snapper) and Clinical Microbiology (Dr Doern) and the Division of Infectious Diseases (Dr Doern), University of Massachusetts Medical Center, Worcester.

Arch Intern Med. 1988;148(5):1064. doi:10.1001/archinte.1988.00380050070012

• A patient with persistent diarrhea was found to have biopsy-proved colitis with large numbers of the protozoan Blastocystis hominis present in stool. Extensive evaluation failed to reveal any other potential etiologic agent of acute colitis. Following treatment with a course of metronidazole, the patient became asymptomatic, B hominis was no longer present in stool, and results of a repeated biopsy were normal. These observations are consistent with the role of B hominis as a gastrointestinal pathogen.

(Arch Intern Med 1988;148:1064)