May 1988

Is Leishmania Infantum an Opportunistic Parasite in Patients With Anti—Human Immunodeficiency Virus Antibodies?

Author Affiliations

Nice, France

Arch Intern Med. 1988;148(5):1228. doi:10.1001/archinte.1988.00380050232032

To the Editor.  Leishmania infantum is the agent of an endemic anthropozoonosis in the Alpes-Maritimes department of France.1 We report two cases of Mediterranean visceral leishmaniasis with anti—human immunodeficiency virus (anti-HIV) antibodies; at least one of the patients has acquired immunodeficiency syndrome (AIDS).

Report of Cases. 

—Case 1.  —A 39-year-old homosexual man was admitted for fever, diarrhea, and weight loss. He showed multiple enlarged lymph nodes and splenomegaly. Laboratory studies were as follows: white blood cell count, 3.3×10109/L (3300/mm3); lymphocytes, 0.45×10109/L (450/mm3); hemoglobin, 5.9 mmol/L (5.9 g/dL); platelet count, 75×10109/L (75/mm3); gammaglobulin, 35 g/L (3.5 g/dL); anti-HIV antibodies, positive (enzymelinked immunosorbent assay [ELISA], Pasteur Institute, and Western blot); and T4 cell count, 0.04× 109/L (4/mm3). Salmonella enteritidis was found in blood cultures, and Pneumocystis carinii was found in bronchoalveolar lavage specimens. Improvement was obtained with

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