• Wegener's granulomatosis has traditionally been treated with steroids and cyclophosphamide. However, sulfamethoxazole-trimethoprim has been shown to be effective. We used it to treat a patient with this disease who had pulmonary Infiltrates, sinusitis, and evidence of renal disease manifested by hematuria and red cell casts. After two months of therapy with sulfamethoxazole-trimethoprim, his hematologic and radiologic values returned to normal.
(Arch Intern Med 1988;148:2065-2066)
Spiera H, Lawson W, Weinrauch H. Wegener's Granulomatosis Treated With Sulfamethoxazole-TrimethoprimReport of a Case. Arch Intern Med. 1988;148(9):2065–2066. doi:10.1001/archinte.1988.00380090125028