December 1988

Myasthenia Gravis After General Anesthesia and Hepatitis B Vaccine

Author Affiliations

From the Department of Pharmacology, Faculty of Medicine, University of Montreal (Dr Biron); School of Occupational Health, McGill University, Montreal (Dr Infante-Rivard); and Pasteur Institute, Lyon, France (Dr Léry). Dr Montpetit is a general practitioner in Montreal.

Arch Intern Med. 1988;148(12):2685. doi:10.1001/archinte.1988.00380120123025

• A 48-year-old man presented with the first symptoms of myasthenia gravis one month after a genera! anesthesia and a second dose of hepatitis B plasma vaccine. Whether either event may have acted as a nonspecific challenge to the patient's immune system is speculative, but the case is described to discover similar observations, if any.

(Arch Intern Med 1988;148:2685)