March 1989

Endemic Fluorosis With Spinal Cord CompressionA Case Report and Review

Author Affiliations

From the Department of Medicine, University of Oklahoma Health Sciences Center and Veterans Administration Medical Center, Oklahoma City.

Arch Intern Med. 1989;149(3):697-700. doi:10.1001/archinte.1989.00390030143028

• We report a case of spinal cord compression in a Mexican immigrant due to vertebral osteosclerosis from chronic fluoride intoxication. Endemic fluorosis is acquired through drinking water. Groundwater sources with high fluoride content occur worldwide. The epidemiology, metabolism, and clinical features of fluorosis are reviewed. Greater physician awareness of this entity is important to identify correctly patients with this unusual and potentially devastating clinical disorder.

(Arch Intern Med 1989;149:697-700)