• A field study on respiratory muscle function and basic pulmonary mechanics was conducted at an international convention of 200 individuals with Charcot-Marie-Tooth disease. Forty patients with respiratory symptoms were evaluated; 15 had significant respiratory muscle dysfunction and 25 were normal. The results suggest that proximal upper limb involvement in individuals with Charcot-Marie-Tooth disease is a simple but significant predictor of respiratory muscle dysfunction.
(Arch Intern Med. 1989;149:1389-1391)
Nathanson BN, Yu D, Chan CK. Respiratory Muscle Weakness in Charcot-Marie-Tooth DiseaseA Field Study. Arch Intern Med. 1989;149(6):1389-1391. doi:10.1001/archinte.1989.00390060109023