March 1990

Acute Tubulointerstitial Nephritis With Uveitis

Author Affiliations

Sapporo, Japan

Arch Intern Med. 1990;150(3):688. doi:10.1001/archinte.1990.00390150154036

To the Editor. —We read Rosenbaum's1 article with interest. Reports of acute tubulointerstitial nephritis with uveitis as a separate entity have increased recently.2 A 15-year-old girl was referred to us because of anterior uveitis, intermittent proteinuria, and glucosuria. Two months before admission, she first complained of sore eyes. An ophthalmologist diagnosed her condition as bilateral anterior uveitis, which gradually improved with topical steroid treatment and relapsed over the following month. During followup, she was also found to have intermittent mild proteinuria and glucosuria. On admission, results of a physical examination were unremarkable, except for red eyes and moderate obesity. Laboratory test results revealed an erythrocyte sedimentation rate of 33 mm/h, normochromic normocytic anemia of 102 g/L, a leukocyte count of 0.06 x 109/L, with 0.59 segmented polymorphonuclear leukocytes, 0.31 lymphocytes, 0.5 monocytes, and 0.5 eosinocytes. The serum creatinine level was 79.6 µmol/L and the serum urea

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