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Article
January 1991

Incorrect Dosage in Editorial

Arch Intern Med. 1991;151(1):93. doi:10.1001/archinte.1991.00400010109015

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Abstract

In the editorial entitled "Prevention of Bacterial Endocarditis" that appeared in the December 1990 issue of the ARCHIVES (Arch Intern Med. 1990;150:2447-2448), an error appeared in the drug dosage given on page 2448, first column, lines 4 through 14. The text appeared as follows: "The new regimen for prevention of bacterial endocarditis in patients undergoing genitourinary and/or gastrointestinal procedures is the following: (1) ampicillin, 2 g intravenously or intramuscularly, plus gentamicin, 1.5 g intravenously 30 minutes before the procedure followed by amoxicillin, 1.5 g 6 hours later; and (2) for penicillin-allergic individuals, vancomycin, 1 g intravenously over 1 hour, plus gentamicin, 1.5 mg intravenously or intramuscularly 1 hour before the procedure, with one repeated dose 8 hours after initial dose." The dosage of gentamicin given for prevention of bacterial endocarditis in patients undergoing genitourinary and/or gastrointestinal procedures was not correctly stated. The dosage should be 1.5 mg/kg (not to

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