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May 1991

The Use of Albumin in Clinical Practice

Author Affiliations

From the Department of Pharmacy Practice, College of Pharmacy (Drs Erstad and Gales), and the Department of Surgery, College of Medicine (Dr Rappaport), University of Arizona, Tucson.

Arch Intern Med. 1991;151(5):901-911. doi:10.1001/archinte.1991.00400050051011

The use of albumin in the clinical setting continues to generate controversy. Periodic shortages and the high cost of albumin have compelled many hospitals to develop guidelines regarding albumin administration. Our purpose is to review the human studies involving albumin. Particular emphasis will be placed on comparative trials involving albumin and the less expensive crystalloid solutions. It is hoped that this review will assist the clinician in making judgments concerning the appropriate use of albumin.

(Arch Intern Med. 1991;151:901-911)