September 1992

Empty Sella Resulting From the Spontaneous Resolution of a Pituitary Macroadenoma

Author Affiliations

From the Department of Medicine, Division of Endocrinology and Metabolism, National Naval Medical Center, Bethesda, Md.

Arch Intern Med. 1992;152(9):1920-1923. doi:10.1001/archinte.1992.00400210140024

Recent studies suggest that the infarction of a pituitary adenoma may be a frequent cause of an empty sella turcica. However, to date, evidence of such progression has been largely speculative. We present the case of a patient with a pituitary macroadenoma that underwent spontaneous involution resulting in an empty sella, as documented by serial magnetic resonance imaging scans. A brief review of the proposed causes of primary empty sella, with emphasis on pituitary necrosis, is provided.

(Arch Intern Med. 1992;152:1920-1923)