May 23, 1994

Iodine Poisoning Secondary to Long-term Iodinated Glycerol Therapy

Author Affiliations

From the Department of Medical Education, Saint Margaret Memorial Hospital, Pittsburgh, Pa (Dr Geurian); and Healthcare for the Homeless Project Inc, Washington, DC (Dr Branam).

Arch Intern Med. 1994;154(10):1153-1156. doi:10.1001/archinte.1994.00420100140018

Iodinated glycerol is used as a mucolytic agent in the treatment of chronic obstructive pulmonary disease. Its efficacy is controversial, and reports of its toxicity are substantial. We report a case of chronic iodine poisoning in a patient with chronic obstructive pulmonary disease following 20 years of iodinated glycerol therapy. Reevaluation of the long-term use of this medication is encouraged. Monitoring long-term recipients of iodinated glycerol therapy for chronic iodine poisoning and drug-induced thyroid abnormalities is recommended.

(Arch Intern Med. 1994;154:1153-1156)