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March 10, 1997

Cutaneous Infections Due to Acanthamoeba in Patients With Acquired Immunodeficiency Syndrome

Author Affiliations

From the Division of Infectious Diseases (Drs Chandrasekar and Crane) and the Departments of Medicine (Drs Chandrasekar, Nandi, and Crane) and Pathology (Dr Fairfax), Wayne State University School ofMedicine, Detroit, Mich.

Arch Intern Med. 1997;157(5):569-572. doi:10.1001/archinte.1997.00440260137017

We report 2 cases of cutaneous Acanthamoeba infection in patients with acquired immunodeficiency syndrome. The disease, which manifests as subcutaneous nodules, mimics other more commonly encountered clinical entities. A high index of suspicion, familiarity with the clinical and histologic appearance of skin lesions, and communication between clinicians and pathologists are crucial for early diagnosis and treatment of this potentially fatal infection.

Arch Intern Med. 1997;157:569-572