We have read with interest the article by Schulz et al1 on the association between depression and mortality in older adults. The authors conclude that high levels of depressive symptoms are an independent risk factor for mortality in community-residing older adults.
We would like to contribute to this topic by presenting data of a study2 carried out in Italy and taking into account 2 important aspects that Schulz et al1 seem to have disregarded, ie, disability and cognitive impairment. In fact, these clinical conditions are known to be associated with both depression and mortality and are also confounders of the association between depression and mortality.
Rozzini R, Sabatini T, Frisoni GB, Trabucchi M. Association Between Depressive Symptoms and Mortality in Elderly People. Arch Intern Med. 2001;161(2):299-300. doi: