The observation by Ferketich et al1 that patients with depression are more likely than members of the general population to develop coronary heart disease has now been proven in both men and women. Previously, the link had been demonstrated in men only. This universal manifestation has never been associated with a neurophysiological basis, yet I believe some studies may suggest one.
Irani SR. Psychological Heart Disease?. Arch Intern Med. 2001;161(3):485–486. doi: