Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001
Statins are highly effective in the treatment of hypercholesterolemia, an effect that is hampered by adverse reactions,1 such as rhabdomyolysis, which may threaten a patient's life.2 Newer statins, such as cerivastatin sodium, are administered in dosages that are much lower than the older statins, such as pravastatin sodium, lovastatin, or simvastatin. It is said that the reduced amount of active product leads to a lower incidence of adverse reactions and preserves the cholesterol-lowering effect3; as a result, no cases of rhabdomyolysis associated with cerivastatin therapy have been described.
Garcia-Valdecasas-Campelo E, Gonzalez-Reimers E, Lopez-Lirola A, Rodriguez-Rodriguez E, Santolaria-Fernandez F. Acute Rhabdomyolysis Associated With Cerivastatin Therapy. Arch Intern Med. 2001;161(6):893. doi: