We read with interest the retrospective cohort analysis by Mary-Claire Roghmann1 discussing the clinical predictors of bacteremia with methicillin-resistant Staphylococcus aureus (MRSA) and the impact of inadequate initial empiric therapy on survival. This study indicated that the strongest predictor for MRSA bacteremia was prior colonization or infection with MRSA, with a relative risk of 4.1. In light of this increased risk, we wish to highlight 2 cases of S aureus bacteremia seen at our institution over the past year, which demonstrate that patients with a prior MRSA infection (particularly bacteremia) may deserve special management considerations.
Sakoulas G, Degirolami PC, Gold HS. Methicillin-Susceptible Staphylococcus aureus: Believe It, or Not. Arch Intern Med. 2001;161(9):1237. doi: