Pérez et al1 recently reported the high proportion of patients with poorly controlled type 1 diabetes mellitus who manifest low levels of high-density lipoprotein cholesterol and high levels of low-density lipoprotein cholesterol. These abnormalities improved with intensified insulin therapy, which the authors suggested obviated the need for other pharmacologic and nonpharmacologic treatment of dyslipidemia. Further, they advocate that intensive insulin therapy be considered the initial treatment of choice for dyslipidemia associated with poorly controlled type 1 diabetes mellitus.
Ansell BJ. Appropriate First-Line Lipid-Lowering Therapy for Type 1 Diabetes Mellitus. Arch Intern Med. 2001;161(11):1461. doi: