Cerebellar degeneration associated with human immunodeficiency (HIV) infection in the absence of cognitive impairment is exceedingly rare. To date, this association has been the subject of a few reports, representing mostly anecdotal findings. A causative association has been postulated, although significant debate continues over whether or not cerebellar degeneration is actually a complication of HIV infection. We describe an HIV-positive patient with subacute cerebellar syndrome in the absence of any cognitive impairment or alternative cause of cerebellar degeneration.
Kwakwa HA, Ghobrial MW. Primary Cerebellar Degeneration and HIV. Arch Intern Med. 2001;161(12):1555-1556. doi: