Bupropion (Wellbutrin; Glaxo Welcome Inc, Triangle Park, NC) is a popular antidepressant commonly used for the treatment of nicotine addiction. Common adverse effects include dose-related seizure disorders and other neuropsychiatric disturbances.1 A search of the literature did not disclose any published work linking the use of bupropion with the development of erythema multiforme.
Carrillo-Jimenez R, Zogby M, Treadwell TL. Erythema Multiforme Associated With Bupropion Use. Arch Intern Med. 2001;161(12):1556. doi: