September 1958

A Study of Heart Disease in One Hundred Eight Hospitalized Patients Dying with Portal Cirrhosis

AMA Arch Intern Med. 1958;102(3):405-413. doi:10.1001/archinte.1958.00030010405009

The general status of the cardiovascular system in portal cirrhosis has been referred to in many excellent studies. It would appear from these studies that moderate to severe coronary arteriosclerosis is less common in patients with portal cirrhosis up to the age of 55 years than in patients without portal cirrhosis.5 The incidence of hypertension associated with portal cirrhosis has been recorded as less than that in a similar age group without portal cirrhosis,3,5,6 although there is not complete agreement on this point.4 Although not stated implicitly in these studies, it is suggested that serious heart disease may be less common in patients with portal cirrhosis than in the normal population.

Materials and Methods  In order to assess the incidence and type of heart disease in patients with portal cirrhosis, 108 consecutive patients who died with portal cirrhosis and were autopsied were studied. It should be noted that the patients did not all