Sarcodosis is a relatively common disease, but involvement of the nervous system
is rare and involvement of the spinal cord
is almost a curiosity. Colover,2 in reviewing the world literature, found 115 cases
of involvement of the nervous system and
added 3 of his own. In the majority of
these cases, uveoparotid fever was present
with paralysis or paresis of the facial nerve.
However, other cranial nerves, peripheral
nerves, meninges, pituitary, hypothalamus,
and brain were sometimes affected. Changes
in the cerebrospinal fluid have repeatedly
been reported. Occasionally, the syndrome
of Guillain-Barré has been observed.
Colover found only one case of involvement of the spinal cord. This case was
described by Reisner,8 who mentions
among 35 cases of Boeck's sarcoidosis "one
male negro patient who presented findings
pointing to a lesion in the sacral segment
of the spinal cord. Complete disappearance
of the neurological symptoms occurred in
the course of observation."
Moldover A. Sarcoidosis of the Spinal Cord. AMA Arch Intern Med. 1958;102(3):414-417. doi:10.1001/archinte.1958.00030010414010