A deficiency of vitamin B12 may
result from several causes.
These include the absence of gastric
intrinsic factor, impaired absorption
of vitamin B12 due to abnormal bacterial overgrowth of the small bowel,
and impaired transport of vitamin
B12 due to a diseased terminal ileum.
It is not generally appreciated that
impaired vitamin B12 absorption may
also be associated with pancreatic
insufficiency.1-5 The present report
describes studies in a patient with
pancreatic insufficiency and vitamin
B12 malabsorption in whom impaired
absorption of vitamin B12 was corrected by treatment with pancreatic
LeBauer E, Smith K, Greenberger NJ. Pancreatic Insufficiency and Vitamin B12 Malabsorption. Arch Intern Med. 1968;122(5):423-425. doi:10.1001/archinte.1968.00040010423009