Clinical Notes
November 1968

Papillary Necrosis due to Candida albicans in a Renal Allograft

Arch Intern Med. 1968;122(5):441-444. doi:10.1001/archinte.1968.00040010441013

Candida infection of the kidney is a common complication of systemic candidiasis.1-3 The usual route of infection is via the blood with production of renal abscesses,2 but rarely local infection occurs in the renal pelvis and ureter, sometimes producing a fungus ball.4,5 Three cases of papillary necrosis due to Candida have been reported.2,6,7 Corticosteroids, immunosuppressive drugs, antibiotics, diabetes mellitus, and neoplastic diseases favor the development of Candida infection and its dissemination. The present patient developed papillary necrosis due to C albicans in a cadaver renal allograft. To our knowledge, this is the first report of this rare, but not unexpected, complication in a transplanted kidney.