About a year ago Wolff-Eisner1 in Berlin, and Calmette2 in Paris, published almost simultaneously articles on the use of tuberculin in the eye as a diagnostic aid in the treatment of tuberculosis.
Since that time the work has been reviewed and repeated by many, both clinicians and pathologists, with considerable divergence of opinion as to its value. Therefore, it seems well to add to the literature any considerable number of cases.
The use of hypodermic injections of old tuberculin (Koch) for diagnostic purposes has been well tested for a number of years and its advantages and limitations are fairly well understood. Chief among the latter have been its inapplicability in pyrexial cases and the general malaise and discomfort attending a positive reaction. Most important among the former were the local reactions around the tuberculous focus, be it a joint or an apex of a lung. It
FRISSELL LF, INGEN PV. THE OCULAR TUBERCULIN REACTION.. Arch Intern Med (Chic). 1908;II(2):176-184. doi:10.1001/archinte.1908.00050070077007