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March 1909

STUDIES IN INACCESSIBLE INTERNAL HEMORRHAGESI. THE EFFECT OF ADRENALIN ON INTESTINAL HEMORRHAGE

Arch Intern Med (Chic). 1909;III(2):139-158. doi:10.1001/archinte.1909.00050130050004
Abstract

I. INTRODUCTION  From a therapeutic point of view hemorrhages may be classified as accessible, i. e., those that can be directly influenced by drugs and inaccessible, i. e., those that can be influenced by drugs only through the circulation. In the former class come hemorrhages from the mouth, nose, throat, eye, wounds, etc., and such internal hemorrhages as can be reached by topical applications, viz., those from the uterus, urethra, bladder, stomach, rectum, etc. In the latter class may be listed intestinal, pulmonary, renal, uterine and cerebral hemorrhages.The value of adrenalin in accessible hemorrhages is well recognized, but so far its use in inaccessible hemorrhages has been condemned rather than commended by our best therapeutists. The chief reason for this is the fact that adrenalin, when introduced into the vascular system, not only causes an active constriction at the point of bleeding, but also raises the

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