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Article
May 1912

THE DIAGNOSIS OF COMPLETE ABSENCE OF PANCREATIC SECRETION FROM THE INTESTINE, WITH THE RESULTS OF DIGESTION AND ABSORPTION EXPERIMENTS

Author Affiliations

NEW HAVEN, CONN.

Arch Intern Med (Chic). 1912;IX(5):525-550. doi:10.1001/archinte.1912.00060170002001
Abstract

The absence of pancreatic secretion is due, in the great majority of instances, to obstruction of the pancreatic ducts, rarely to atrophy of the secretive cells. It is the purpose of the first part of this article to show that while the diagnosis of many diseases of the pancreas is difficult, that of complete absence of the secretion is usually an easy matter without the use of time-consuming laboratory measures, simply by the inspection and microscopical examination of the feces. The second part will deal with my results in digestion and absorption experiments undertaken in cases of exclusion of the pancreatic juice from the intestine, both with and without icterus, with the effect of the administration of pancreatic preparations, and of hydrochloric acid in this condition, with the literature of the subject and the conclusions that may be drawn from such work. There will be also a

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