This study was undertaken for two reasons. First, we wished to determine whether it were possible to make an accurate study of the metabolism of a rational bed patient in the hospital ward available to us, without the assistance of a special nurse. Second, to determine whether or not a study of the mineral exchange would yield any information of value concerning scurvy, a disease which may be eventually regarded as a disturbance of metabolism.Our first question can be answered in the affirmative. If an intelligent ward nurse, an interested intern and the usual hospital facilities are available, a metabolic experiment such as the one described by us, is possible.The methods employed were for the most part tested on standard solutions and modified when necessary to meet experimental conditions and increase their accuracy.
An exhaustive study of the Index Medicus and Surgeon General's Catalogue
BAUMANN L, HOWARD CP. METABOLISM OF SCURVY IN AN ADULT. Arch Intern Med (Chic). 1912;IX(6):665-679. doi:10.1001/archinte.1912.00060180027003