January 1910


Arch Intern Med (Chic). 1910;V(1):1-5. doi:10.1001/archinte.1910.00050230004001

In the text-books on pathology a lesion of the liver is described in which the liver cells around the hepatic veins are atrophied and wanting, and the blood spaces are distended and filled with blood. This condition is generally supposed to result from continued pressure on the liver cells due to passive congestion. This continued pressure causes the cells to atrophy and disappear.

Mallory1 describes a hemorrhagic type of necrosis. In this type an exudate into the spaces occupied by the necrotic liver cells is composed chiefly of red-blood corpuscles. These dilated spaces filled with redblood corpuscles give the appearance of dilated sinusoids (especially when the necrotic liver cells have more or less disappeared). As a matter of fact, the sinusoids in these cases are practically empty and collapsed.

As a result of recent histologic study of a series of cases Mallory2 reports that the type of

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