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Article
January 1910

THE PECULIARITIES OF NITROGENOUS METABOLISM IN PERNICIOUS VOMITING OF PREGNANCY

Author Affiliations

NEW HAVEN

From the Sheffield Laboratory of Physiological Chemistry, Yale University, and from the Obstetrical Service of New Haven Hospital.

Arch Intern Med (Chic). 1910;V(1):61-91. doi:10.1001/archinte.1910.00050230064007
Abstract

THE CLINICAL PICTURE PRESENTED BY PERNICIOUS VOMITING OF PREGNANCY  According to the classification of Williams,1 pernicious vomiting of pregnancy may be of two types, one acute, the other chronic. In the acute form death may result within a relatively short period of time. The patient, who has been apparently a normal pregnant woman, suffering from what appeared to be the ordinary "morning sickness," suddenly begins to vomit all food. This symptom is soon followed by signs of prostration, unaccompanied by an increased pulse-rate or rise of temperature. After this condition has been maintained for a number of days considerable quantities of a coffee-ground-like material may be vomited at frequent intervals. The patient soon passes into a torpid state, leading to coma and resulting in death. This type of vomiting is not necessarily associated with great emaciation. The urine, which is apparently normal during the first days of pregnancy,

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