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Article
February 1911

THE AMEBOID ACTIVITY OF MEGALOBLASTS

Arch Intern Med (Chic). 1911;VII(2):223-225. doi:10.1001/archinte.1911.00060020088005

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Abstract

In the study of the blood and blood-forming organs so much attention has been given to methods of fixation and staining that the careful examination of the fresh specimen or tissue is too often neglected. Certain biological characteristics of the cells, such, for instance, as ameboid activity, may easily be overlooked.

In the study of the blood of a case of Addisonian anemia of a chronic course, I have observed characteristic ameboid movements in a megaloblast. Phylogenetically, it is not remarkable that a megaloblast should possess the powers of ameboid activity; indeed, one might expect that this should be so. Inasmuch, however, as the present observation is apparently the first of this nature, it would appear to be worthy of record.

History.  —R., aged 39, a patient of Dr. G. A. Hartman, consulted me on Sept. 27, 1905. His family, personal history and habits were excellent.

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