Medical literature during the past five years has contained numerous reports of chronic typhoid bacillus-carriers, but there has been very little discussion of the treatment of these patients. The reason for this paucity appears to be that treatment has been unsatisfactory, and in but few cases has the infection been eradicated.
Dehler1 has cured by cholecystostomy two patients who discharged the bacilli in the feces, but the bacilli did not disappear from the stools of a paratyphoid carrier on whom Forster2 did cholecystostomy for gallstones. Grimme3 reported the recovery of an intestinal typhoid carrier on whom cholecystectomy was done. Park4 failed to eradicate the infection in "Typhoid Mary," an intestinal carrier, by the use of intestinal antiseptics and hexamethylenamin; the latter drug was given in doses of 100 to 150 grains daily. Park cites Lentz, who stated that he could not get rid of
BREM WV, WATSON FC. RECOVERY OF A TYPHOID BACILLUS-CARRIER DURING VACCINE TREATMENT. Arch Intern Med (Chic). 1911;VIII(5):630-638. doi:10.1001/archinte.1911.00060110076007