The introduction within recent years of numerous organic iodin compounds as substitutes for the iodids, the extravagant claims made for some of them by the manufacturers, both as regards therapeutic efficiency and absence of toxic side actions, and the scarcity of literature on the subject in American periodicals seem to demand a review of the entire subject of the value of these substances as therapeutic agents. Most of these compounds have originated from German manufacturers, and nearly all of the investigations regarding them have been published in that country. These substances, however, are being rapidly introduced into the American market, and at the suggestion of the Council on Pharmacy and Chemistry of the American Medical Association, I have undertaken an investigation of the pharmacological basis for the use of such compounds as substitutes for the iodids. The present paper deals chiefly with the literature on the subject.
McLEAN FC. ORGANIC IODIN PREPARATIONS, THEIR PHARMACOLOGY AND THERAPEUTIC VALUE. Arch Intern Med (Chic). 1912;X(5):505-520. doi:10.1001/archinte.1912.00060230102008