January 1913


Arch Intern Med (Chic). 1913;XI(1):15-51. doi:10.1001/archinte.1913.00060250022002

For some years I have been much interested in the condition which is now generally known as syphilitic aortitis or mesaortitis. At first my observations were particularly directed to the pathological lesion itself ; later the exact etiology of these changes became the subject for study, while at present it is the diagnosis and treatment of the disease to which most time is devoted. Up to the present I have had an opportunity at the Pennsylvania1 and University hospitals in Philadelphia, and at the Presbyterian Hospital in New York of studying sixty-three cases in which syphilitic aortitis was proved to exist at autopsy, or in which the diagnosis seemed reasonably sure from the combination of certain symptoms and signs, with a positive Wassermann reaction during life. Of the entire number, twenty have been treated with salvarsan. But except for the fact that the diagnosis and treatment of this disease

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