Rowlands,1 in his examination of twenty-two stones, came to the following conclusions: that renal calculi are composed almost entirely of calcium oxalate; that uric acid is almost always absent, or present in very small traces; that phosphates are commonly present.
Mackarell, Moore and Thomas,2 following the investigations of Rowlands, concluded that these results have a marked bearing on the calcium metabolism in gout and allied conditions. They examined twenty-four renal stones and they corroborated the findings of Rowlands. They recommended that when a calculus has been obtained by operation or otherwise, it should be analyzed, and if it is found to be composed of calcium salts, the patient should be put on a course of acid treatment and not alkaline medications, as has been the custom.
I have examined a series of sixteen stones from patients of the Mount Sinai and various other hospitals in New York
KAHN M. STUDY OF THE CHEMISTRY OF RENAL CALCULI. Arch Intern Med (Chic). 1913;XI(1):92-99. doi:10.1001/archinte.1913.00060250099006