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Article
March 1913

CONCERNING THE PRESENCE OF HEMOLYSINS IN STOOL EXTRACTS

Author Affiliations

PHILADELPHIA

Arch Intern Med (Chic). 1913;XI(3):300-304. doi:10.1001/archinte.1913.00060270054004
Abstract

The following experiments were undertaken with the aim of ascertaining, if possible, whether extracts of stools from cases of essential progressive pernicious anemia contain hemolysing substances not found in normal stools, nor in stools from other diseases. If repeatedly present, this could be regarded as of some use as a further step in the clinical diagnosis of a disease the etiology of which is still uncertain and the classification of which is hardly satisfactory.

In reviewing the literature on hemolysins in the gastro-intestinal tract, I find that while much has been done with tumor and organ extracts, little attention has been paid to the stools.

Korschun and Morganroth,1 in their work on the hemolytic action of organ extracts, describe a hemolysin thus derived, which is active against the blood-cells of the same species and possesses the following characteristics: coctostabile, soluble in alcohol, not complex, and inactive in causing

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