Numerous studies have established a definite relationship between the symptoms usually referred to as Adams-Stokes disease and changes in the auriculoventricular bundle of the heart, the bundle of His. The absence of sufficient information in many of the reports in a recent summary by Bachman1 led him to base this definite relationship on the evidence in only twenty-four of the eighty-six cases reviewed; in the remainder the details were inadequate for comparison.
In these twenty-four, to which I have added a few2 not in the number considered by Bachman, the alterations found in the His bundle were as follows :
From a study of such a table as this it is evident that well-marked examples of the Adams-Stokes syndrome have for their explanation a lesion of the auriculoventricular bundle. A number of careful studies have shown that a complete transverse lesion of the main stem of this conducting
NUZUM F. FATTY INFILTRATION (LIPOMATOSIS) OF THE AURICULOVENTRICULAR BUNDLE OF HIS, WITH SUDDEN UNEXPECTED DEATH. Arch Intern Med (Chic). 1914;XIII(4):640-647. doi:10.1001/archinte.1914.00070100133014