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Article
May 1914

A STUDY OF THE ACTION OF ATROPIN ON THE EOSINOPHIL CELLS OF THE BLOOD

Author Affiliations

NEW YORK

From the Department of Practice of Medicine, College of Physicians and Surgeons, Columbia University, New York.

Arch Intern Med (Chic). 1914;XIII(5):794-802. doi:10.1001/archinte.1914.00070110123007
Abstract

Our knowledge of the functions of the eosinophil cells is slight. The most important and perhaps the only well-demonstrated function of these cells is their association with the reaction of the body to the invasion of alien protein. The notable rise in number of eosinophils in the circulating blood following the parenteral introduction of various proteins is now well known. By the work of Schlecht,1 Schlecht and Schwenker,2 Schittenhelm, Weichardt and Grisshammer,3 Stäubli,4 Herrick,5 and Ahl and Schittenhelm6 it has been thoroughly established that the subcutaneous, intraperitoneal or intravenous introduction of alien proteins at longer or shorter intervals is followed by a definite eosinophilia of the blood. Particularly is this a feature of the postanaphylactic stage following the injection of protein at intervals of five days or more. The eosinophilia following administration of diphtheria antitoxin and of tuberculin has been recognized for a

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