[Skip to Content]
[Skip to Content Landing]
Article
February 1917

THE AGGLUTININS AND COMPLEMENT-FIXING ANTIBODIES IN THE SERUM OF PERSONS VACCINATED AGAINST TYPHOID FEVE

Author Affiliations

SAN FRANCISCO

From the George Williams Hooper Foundation for Medical Research, and the Department of Medicine, University of California Medical School, San Francisco.

Arch Intern Med (Chic). 1917;XIX(2):293-310. doi:10.1001/archinte.1917.00080210134007
Abstract

During the last few years numerous reports have appeared on the value of the Widal reaction in vaccinated persons. Most of these studies suffer from lack of uniformity of technic or from faulty conclusions derived from a study of selected cases only. In the European armies the extensive use of typhoid vaccines of varying antigenic value and different modes of preparation has especially called forth numerous publications on the value of serologic tests as a means of ascertaining the grade of immunity present. Unfortunately, the results are not comparable on account of the diversity of the preparations and of the methods used in the different countries. Most of the writers consider only the agglutination test (their results will be discussed in connection with ours). Felke1 and also Hage and Korff-Petersen,2 however, report as well on the value of the complement fixation test ; thus Felke claims

First Page Preview View Large
First page PDF preview
First page PDF preview
×