In previous articles1 we have reviewed the literature on serum proteins in health and disease, and have presented new values for serum proteins, obtained by Robertson's microrefractometric method, from normal adults and from those suffering with syphilis, pneumonia and other infections. The relation of globulin to the Wassermann reaction as well as the increase of serum proteins due to stasis have also been studied.
Former estimations of serum proteins in chronic diseases, which are referred to in a previous article,2 show in a general way an increase of serum globulin with a decrease of total protein, the latter being most pronounced in hydremia. These results, though, are not uniform, owing to the use of varied technic and methods. We considered it necessary, therefore, to estimate the serum proteins in chronic diseases by the recent microrefractometric method of Robertson3 which we have shown to be dependable and
ROWE AH. REFRACTOMETRIC STUDIES OF SERUM PROTEINS IN NEPHRITIS, CARDIAC DECOMPENSATION, DIABETES, ANEMIA, AND OTHER CHRONIC DISEASES. Arch Intern Med (Chic). 1917;XIX(3):354-366. doi:10.1001/archinte.1917.00080220021003