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Article
January 1915

THE DISTRIBUTION OF IODIN IN THE CELL FOLLOWING ADMINISTRATION OF ORGANIC IODIN PREPARATIONS

Author Affiliations

PORTLAND, ORE.

From the Laboratory of Pharmacology, University of Oregon, Department of Medicine.

Arch Intern Med (Chic). 1915;XV(1):92-97. doi:10.1001/archinte.1915.00070190095006
Abstract

In a previous communication1 results of analyses of tissues were given, showing essential differences in the distribution of iodin in the various constituents of the cell after administration of different iodin preparations. It was believed that a further series of analyses might serve to confirm these results, and throw light on the fate of various organic iodin preparations in the body. It had been previously shown by other investigators that after administration of iodized fats a larger relative proportion of iodin was found in the organs rich in lipoids, such as the brain, spinal cord and liver. Their results had been taken to show that these iodized fats were absorbed in a lipoid soluble form, and were held by the lipoids in the cells. This being the case, these substances should produce a relatively larger amount of iodin in the lipoid fraction, after extraction and separation of the tissue

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